Brian Smith

ISTB-1 rm 322
TEMPE
Trustees of ASU Professor
Faculty
TEMPE Campus
Mailcode
4501

Biography

Brian Smith is an inaugural Trustees of ASU  Professor. He is a behavioral neuroscientist who studies how animals learn about odors in order to predict important events, such as an encounter with food, a mate or predator. His research employs detailed behavioral studies of learning and memory. He and his research team also use a combination of electrophysiological, bioimaging, molecular and computational techniques to directly link changes in behavior to changes in the brain.

Professor Smith’s research focuses on learning and memory systems in both insects and mammals. His work is being applied to studies of human diseases, such as Alzheimer's and Parkinson's, as well as to the negative effects of heavy metal poisoning on learning and memory.

Publications

  • Bazhenov M, Huerta R, Smith BH (2013) A computational framework for understanding decision making through integration of basic learning rules. J Neuroscience 13: 5686-5697. PMID: 23536082
  • Locatelli FF, Fernandez PC, Villareal F, Mezzinoglo K, Huerta R, Galizia CG, Smith BH. (2012) Non-associative plasticity alters competitive interactions among mixture components in early olfactory processing. European J Neuroscience. 37:63-79. Epub 2012 Nov 21. PMID: 23167675
  • Hladun KR, Smith BH, Mustard JA, Morton RR, Trumble JT (2012) Selenium toxicity to honey bee (Apismellifera L.) pollinators: effects on behaviors and survival. PLoS One. 2012;7(4):e34137. Epub  2012 Apr 13. PMID: 22514621.
  • Sinakevitch I, Mustard JA, Smith BH (2011) Distribution of the octopamine receptor AmOA1 in the honey bee brain. PLOS One. 2011 Jan 18;6(1):e14536. PMID: 21267078.
  • Chandra SBC, Wright GW, Smith BH (2010) An analysis of the CS pre-exposure effect in the honeybee, Apismellifera. Anim Cognition 13: 805-815. PMID: 20521073.

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  • Chen JY1, Marachlian E2, Assisi C1, Huerta R3, Smith BH4, Locatelli F5, Bazhenov M6. Learning modifies odor mixture processing to improve detection of relevant components. J Neurosci. 2015 Jan 7;35(1):179-97 (2015).
  • Brian H. Smith1, Christina M. Burden1. A Proboscis Extension Response Protocol for Investigating Behavioral Plasticity in Insects: Application to Basic, Biomedical, and Agricultural Research. Brian H. Smith1, Christina M. Burden1 (2014).
  • Szyszka P1, Gerkin RC2, Galizia CG3, Smith BH2. High-speed odor transduction and pulse tracking by insect olfactory receptor neurons. Proc Natl Acad Sci U S A (2014).
  • Sinakevitch I, Mustard JA, Smith BH. (2011). Distribution of the octopamine receptor AmOA1 in the honey bee brain. PLoSONE (2011).
  • Ahn S, Smith BH, Borisyuk A, Terman D. Analyzing neuronal networks using discrete-time dynamics. Physica D: Nonlinear Phenomena (2010).
  • Chandra SBC, Wright GW, Smith BH. An analysis of the CS preexposure effect in the honeybee, Apis mellifera. Anim Cognition (2010).
  • Drezner-Levy T, Smith BH, Shafir S. The effect of foraging specialization on various learning tasks in the honey bee (Apis mellifera). Behavioral Ecology & Sociobiology (2009).
  • Fernandez PC, Locatelli FF, Rennell N, Deleo G, Smith BH. Reinforcement tunes spatiotemporal dynamics of early olfactory processing. J Neuroscience (2009).
  • Mustard JA, Pham PM, Smith BH. Modulation of motor behavior by dopamine and the D1-like dopamine receptor AmDOP2 in the honey bee. J Insect Physiol (2009).
  • Wiegmann DD, Smith BH. Incentive relativity and the specificity of reward expectations in honey bees. Int J Comparative Psychology (2009).
  • Wright GA, Carlton M, Smith BH. A honeybee’s ability to learn, recognize, and discriminate odours depends upon odour sampling time and concentration. Behavioral Neuroscience (2009).
  • Dacher M, Smith BH. Olfactory Interference during Inhibitory Backward Pairing in Honey Bees. PLoS ONE 3(10) (2008).
  • Heather Mattila, Brian Smith. Learning and memory in workers reared by nutritionally stressed honey bee (Apis mellifera L.) colonies. Physiology & Behavior (2008).
  • Dhruba Naug, Brian Smith. Experimentally induced change in infectious period affects transmission dynamics in a social group. Proceedings of the Royal Society: Bological Sciences (2007).
  • Geraldine Wright, Julie Mustard, Sonya Kottcamp, Brian Smith. Olfactory memory formation and the influence of reward pathway during appetitive learning by honey bees. Journal of Experimental Biology (2007).
  • B Fussnecker, Brian Smith, J Mustard. Octopamine and tyramine influence the behavioral profile of locomotor activity in the honey bee (Apis mellifera). J Insect Physiology (2006).
  • Smith, Brian (Author) ,Wright, G A (Author) ,Daly, K S (Author) . Learning-based recognition and discrimination of floral odors. The Biology and Chemistry of Floral Scents (2006).
  • G Wright, A Lutmerding, N Dudareva, Brian Smith. Intensity and the ratios of compounds in the scent of snapdragon flowers affect scent discrimination by honey bees (Apis mellifera). J. Comparative Physiology (2005).
  • J Latshaw, Brian Smith. Heritable variation in learning performance affects foraging preferences in the honey bee (Apis mellifera). Behavioral Ecology Sociobiology (2005).
  • S Shafir, G Menda, Brian Smith. Caste-specific difference in risk sensitivity in honeybees. Animal Behavior (2005).
  • A Borisyuk, Brian Smith. Odor interactions and learning in a model of the insect antennal lobe. Neurocomputing (2004).
  • G Wright, Brian Smith. Different thresholds for detection and discrimination of odors in the honeybee (Apis mellifera). Chemical Senses (2004).
  • K Daly, G Wright, Brian Smith. Molecular features of odorants systematically influence slow temporal responses across clusters of coordinated antennal lobe units in the moth Manduca sexta. J. Neurophysiology (2004).
  • T Farooqui, H Vaessin, Brian Smith. Octopamine receptors in the honeybee (Apis mellifera) brain and their disruption by RNA-mediated interference. Journal of Insect Physiology (2004).
  • Daly, K, Christensen, T, Lei, H, Smith, Brian, Hildebrand, J. Learning modulates the ensemble representations for odors in primary olfactory networks. (2004).
  • Wright, G, Smith, Brian. Variation in complex olfactory stimuli and its influence on odour recognition. (2004).
  • T Farooqui, K Robinson, H Vaessin, Brian Smith. Modulation of early olfactory processing by an identified octopaminergic reinforcement pathway in the honeybee. J. Neuroscience (2003).
  • G Wright, B Skinner, Brian Smith. Ability of honeybee, Apis mellifera, to detect and discriminate odors of varieties of canola (Brassica rapa and Brassica napus) and snapdragon flowers (Antirrhinum majus). J Chem. Ecol (2002).
  • S Shafir, T Waite, Brian Smith. Context-dependent violations of rational choice in honeybees (Apis mellifera) and gray jays (Perisoreus canadensis). Behav. Ecology Sociobiology (2002).
  • C Chandra, G Hunt, Brian Smith. Quantitative trait loci associated with reversal learning and latent inhibition in honeybees (Apis mellifera). Behavior Genetics (2001).
  • H Ferguson, S Cobey, Brian Smith. Sensitivity to a change in reward is heritable in the honey bee, Apis mellifera. Animal Behaviour (2001).
  • K Daly, C Chandra, M Durtschi, Brian Smith. Generalization of olfactory-based conditioned response reveals unique but overlapping odour representations in the moth, Manduca sexta. J. Experimental Biology (2001).
  • K Daly, M Durtschi, Brian Smith. Olfactory-based discrimination learning in the moth, Manduca sexta. J. Insect Physiology (2001).
  • C Chandra, J Hosler, Brian Smith. Heritable variation for latent inhibition and its correlation to reversal learning in the honey bee, Apis mellifera. J. Comparative Psychology (2000).
  • J Hosler, Brian Smith. The intensity of blocking in odor mixtures is dependent on the identities of the odorants. J. Experimental Biology (2000).
  • J Hosler, K Buxton, Brian Smith. Differential impairment of olfactory discrimination by blockade of GABA and nitric oxide activity in the honey bee antennal lobes. Behavioral Neuroscience (2000).
  • K Daly, Brian Smith. Associative olfactory conditioning of the moth, Manduca sexta. J. Experimental Biology (2000).
  • K Robinson, H Ferguson, S Cobey, H Vaessin, Brian Smith. Sperm-mediated transformation of the honey bee, Apis mellifera. Insect Molecular Biology (2000).
  • R Masterman, Brian Smith, M Spivak. Brood odor discrimination abilities in hygenic honey bees (Apis mellifera L.) using proboscis extension reflex conditioning. J Insect Behavior (2000).
  • Y Ben-Shahar, C Thompson, S Hartz, Brian Smith, G Robinson. Performance on a reversal test is associated with division of labour in the honeybee, Apis mellifera. Animal Cognition (2000).
  • Y-S Kim, Brian Smith. Effect of an amino acid on feeding preferences and learning behavior in the honey Bee, Apis mellifera. J. Insect Physiology (2000).

Research Activity

Courses

Spring 2022
Course Number Course Title
BIO 477 Systems & Behavioral Neuro
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
MBB 495 Undergraduate Research
BIO 495 Undergraduate Research
Fall 2021
Course Number Course Title
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 495 Undergraduate Research
AML 592 Research
ANB 602 Current Issues In Behavior
Summer 2021
Course Number Course Title
BIO 495 Undergraduate Research
Spring 2021
Course Number Course Title
BIO 360 Animal Physiology
BIO 394 Special Topics
BIO 477 Systems & Behavioral Neuro
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
MBB 495 Undergraduate Research
BIO 495 Undergraduate Research
BIO 591 Seminar
Fall 2020
Course Number Course Title
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 495 Undergraduate Research
Summer 2020
Course Number Course Title
BIO 495 Undergraduate Research
Spring 2020
Course Number Course Title
BIO 360 Animal Physiology
BIO 394 Special Topics
BIO 477 Systems & Behavioral Neuro
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
MBB 495 Undergraduate Research
BIO 495 Undergraduate Research
Fall 2019
Course Number Course Title
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
MBB 495 Undergraduate Research
BIO 495 Undergraduate Research
Summer 2019
Course Number Course Title
BIO 495 Undergraduate Research
Spring 2019
Course Number Course Title
BIO 360 Animal Physiology
BIO 394 Special Topics
BIO 400 Topics in Neuroscience
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
MBB 495 Undergraduate Research
BIO 495 Undergraduate Research
Fall 2018
Course Number Course Title
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 495 Undergraduate Research
Summer 2018
Course Number Course Title
BIO 495 Undergraduate Research
Spring 2018
Course Number Course Title
BIO 360 Animal Physiology
BIO 400 Topics in Neuroscience
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 494 Special Topics
BIO 495 Undergraduate Research
BIO 598 Special Topics
Fall 2017
Course Number Course Title
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 495 Undergraduate Research
NEU 555 Adv Molecular & Cellular Sci
MCB 555 Adv Molecular & Cellular Sci
Summer 2017
Course Number Course Title
BIO 495 Undergraduate Research

Service

  • PNAS J Comp Physiol PLoSOne Zukunftskolleg NSF CRCNS NIH BRAIN PRS-B Anim Beh Current Biol, Reviewer (2014 - Present)
  • NIH NICHD, Site visit for intramural research program (2011 - Present)
  • School of Life Sciences, Director (2011 - Present)
  • NIH NIDCD, grant review (2011 - Present)
  • PLOSOne, Reviewer (2011 - Present)
  • Current Biology, Reviewer (2011 - Present)
  • NSF, Grant proposal review (2011 - Present)
  • National Institutes of Health, Reviewer for grant proposals (2011 - Present)
  • PNAS, Reviewer (2011 - Present)
  • President's Faculty Advisory Committee, member (2011 - Present)
  • Preparing Future Faculty Program, Discussant (2010 - Present)
  • Provost's meeting with Univ of Toledo group, participant (2010 - Present)
  • Faculty Advisory Council for President, member (2010 - Present)
  • Interdisciplinary Graduate Program in Neuroscience, Director (2010 - Present)
  • OISB, Faculty Leader (2010 - Present)
  • Frontier in Neuroscience, Reviewer (2009 - Present)
  • Journal of Comparative Neurology, Reviewer (2009 - Present)
  • Dean's Faculty/Scientific Advisory Committee Keck Lab, member (2009 - Present)
  • Marsden Fund (New Zealand), Reviewer (2009 - Present)
  • NIH S10 proposals, Reviewer (2009 - Present)
  • Faculty Leader OISB, Faculty Leader (2009 - Present)
  • Chemical Senses, Reviewer (2009 - Present)
  • NIH NIDCD Special Emphasis Panel, Reviewer (2009 - Present)
  • Journal of Neuroscience, Reviewer (2009 - Present)
  • National Institutes of Health, Reviewer (2009 - Present)
  • CRCNS France, Reviewer (2009 - Present)
  • National Science Foundation, Reviewer (2009 - Present)
  • Frontiers in Systems Neuroscience, Review Editor/Editorial Board (2008 - Present)
  • NIH-National Inst of Child Health and Development, Program review (2008 - Present)
  • Interdisciplinary Graduate Program in Neuroscience, Director (2008 - Present)
  • Genes, Brain and Behavior, reviewer (2008 - Present)
  • NIH-National Inst of Deafness and other Communication Disorders, Study section (2008 - Present)
  • J Experimental Biology, reviewer (2008 - Present)
  • Journal of Neuroscience, reviewer (2008 - Present)
  • University Promotion & Tenure Committee, Chair (2007 - Present)
  • Center for Adaptive Neural Systems, Executive Committee member (2007 - Present)
  • Interdisciplinary Graduate Program in Neuroscience, Director (2007 - Present)
  • SoLS Promotion & Tenure Committee, (2007 - Present)
  • ASU-BNI 2nd Annual Neuroscience Symposium, Co-organizer (2006 - Present)
  • SOLS, Director (2014 - 2014)
  • IDGP Neuroscience, Director (2011 - 2011)
  • Leadership Fellows Program, Participant (2011 - 2011)
  • OISB/SOLS, Faculty Leader (2011 - 2011)
  • Univ Wuerzburg, Germany, External examiner for Habilitation (2010 - 2010)
  • University of Dunnedin, New Zealand, External thesis examiner (2010 - 2010)
  • University Promotion & Tenure, Chair (2010 - 2010)
  • University Promotion & Tenure Committee, Chair (2009 - 2009)
  • HEXAPODIUM, Organizer (2008 - 2008)
  • University of Califonia Los Angeles, Promotionand tenure review (2008 - 2008)
  • SOLUR, Organized SOLUR program seminar (2008 - 2008)
  • PNAS, Ad hoc reviewer (2006 - 2007)
  • iGEP in Neuroscience and now Neuroscience & Behavior working group, Committee member and now Chair of N&B working group (2006 - 2006)
  • National Institutes of Health, Outside reviewer for site visit at NICHD (2006 - 2006)
  • National Institutes of Health, Ad hoc review Learning & Memory IFCN-7 study section (2006 - 2006)
  • NIH IFCN-7 study section, Ad hoc reviewer (2005 - 2005)
  • NIH BRLE study section, Panel member/reviewer (1998 - 2005)
  • College of Biological Sciences, Member, Promotion & Tenure committee (2001 - 2004)
  • Dean's Advisory Committee, College of Biological Sciences, Member (2001 - 2003)

Expertise Areas