Robin Harris

LSE 342 (Lab), LSE 333 (Office)
Tempe
Asst Professor
Faculty
TEMPE Campus
Mailcode
4501

Biography

Rob Harris is a geneticist and developmental biologist, whose research combines genetic, molecular and imaging techniques to explore the fundamental and complex phenomenon of tissue regeneration.

Using the powerful genetic tools available in the fruit fly Drosophila melanogaster, together with whole genome approaches, his work aims to identify and characterize genomic programs that are activated in response to tissue injury, and use this information to understand why organs and tissues tend to lose the ability to regenerate as they develop. With this knowledge his group ultimately aims to discover novel genetic manipulations that can be used to improve or induce de novo regeneration in non-regenerating tissues.

Education

Rob Harris is received his PhD from the University of Manchester in England, funded by the Biotechnology and Biological Sciences Research Council. He went on to complete his postdoctoral research at the University of California, Berkeley, funded by the California Institute for Regenerative Medicine and the Life Sciences Research Foundation.

Google Scholar

Publications

1.       Harris, R.E., Setiawan, L., Saul, J., Hariharan, I.K. Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs. eLIFE 5, e11588 (2016)

2.       Newton, F.G., Harris, R.E., Sutcliffe, C., and Ashe, H.L. Coordinate post-transcriptional repression of Dpp-dependent transcription factors attenuates signal range during development. Development  142, 3362-73 (2015).

3.       Fritsch, C., Sawala, A., Harris, R., Maartens, A., Sutcliffe, C., Ashe, H.L., and Ray, R.P. Different requirements for proteolytic processing of bone morphogenetic protein 5/6/7/8 ligands in Drosophila melanogaster. The Journal of Biological Chemistry 287, 5942-5953. (2012).

4.       Harris, R.E., and Ashe, H.L. Cease and desist: modulating short-range Dpp signalling in the stem-cell niche. EMBO Reports 12, 519-526. (2011).

5.       Harris, R.E., Pargett, M., Sutcliffe, C., Umulis, D., and Ashe, H.L. Brat promotes stem cell differentiation via control of a bistable switch that restricts BMP signaling. Developmental Cell 20, 72-83. (2011).

6.       Harris, R.E.,Yarunin, A., Ashe, M.P., and Ashe, H.L. Patterning of the Drosophila oocyte by a sequential translation repression program involving the d4EHP and Belle translational repressors. RNA Biology 8, 904-912. (2011).

7.       Wang, X., Harris, R.E., Bayston, L.J., and Ashe, H.L. Type IV collagens regulate BMP signalling in Drosophila. Nature 455, 72-77. (2008).

Courses

Fall 2019
Course Number Course Title
BIO 492 Honors Directed Study
BIO 494 Special Topics
BIO 495 Undergraduate Research
MCB 501 Seminar:Molecular/Cell Biology
BIO 598 Special Topics
MCB 701 Seminar:Molecular/Cellular Bio
Spring 2019
Course Number Course Title
BIO 340 General Genetics
BIO 495 Undergraduate Research
MCB 501 Seminar:Molecular/Cell Biology
MCB 701 Seminar:Molecular/Cellular Bio
Fall 2018
Course Number Course Title
BIO 494 Special Topics
BIO 495 Undergraduate Research
MCB 501 Seminar:Molecular/Cell Biology
BIO 598 Special Topics
MCB 701 Seminar:Molecular/Cellular Bio
Summer 2018
Course Number Course Title
BIO 495 Undergraduate Research